The term “non-psychoactive” refers to a substance that does not significantly alter a person’s mental state, particularly by not inducing the intoxicating effects associated with psychoactive compounds. Such substances do not produce the euphoria, altered perception, or cognitive impairment that are typically associated with psychoactive drugs. This term is often used in the context of cannabinoids, where compounds like cannabidiol (CBD) are described as non-psychoactive in contrast to tetrahydrocannabinol (THC), which is the primary psychoactive component of cannabis. Non-psychoactive substances can still have profound effects on the body, potentially offering therapeutic benefits without the psychoactive experiences that can accompany other drugs. Their non-intoxicating nature makes them more appealing for medical use, especially for patients who require symptom relief without the cognitive changes that might impair their daily activities. It is important to note, however, that the term “non-psychoactive” can be somewhat misleading, as even substances that do not produce a traditional “high” can still affect the mind in subtle ways, such as reducing anxiety or improving mood. Therefore, some researchers prefer to use terms like “non-intoxicating” to more accurately describe these compounds.

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